Determination of colchicine residues in sheep serum and milk using high-performance liquid chromatography combined with electrospray ionization ion trap tandem mass spectrometry

Hamscher, G.(*1), Priess, B.(1), Nau, H.(1), Panariti, E.(2)

(1) Dept. Food Toxicol., Univ. Veterin. Med. Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany, (2) Inst. Veterin. Res., Aleksander Moisiu St. 10, Tirana, Albania

REF: Anal. Chem. 77(8) 2005 2421-2425

MS: Finnigan LCQ, ESP, pos., CAD.

Keywords: Electrospray/MS/MS, drugs; Ion trap; CAD; Colchicine; Alkaloids; Serum; Milk; Colchicum autumnale; Food;

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Identification of the components of 16-membered macrolide antibiotics by LC/MS

Hu, M.(1),Hu, C.-Q.(*2)

(1) Hubei Inst. Drug Control, Wuhan 430064, (2) Natl. Inst. Control Pharm. Biol. Prod., Beijing 100050, PR China

REF: Anal. Chim. Acta 535(1/2) 2005 89-99

MS: Finnigan LCQ Deca XP Plus, ESP, pos., CAD.

Keywords: Electrospray/MS/MS, antibiotics; Ion trap; CAD; Drugs; Macrolide antibiotics; Leucomycins; Spiramycins;

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4-Hydroperoxy-2-nonenal-induced formation of 1,N2-etheno-2'-deoxyguanosine adducts

Lee, S.H., Arora, J.A., Oe, T., Blair, I.A.(*)

Cent. Cancer Pharmacol., Univ. Pennsylvania Sch. Med., Philadelphia, PA 19104-6160, USA

REF: Chem. Res. Toxicol. 18(4) 2005 780-786

MS: Finnigan LCQ, APCI, pos., CAD, MSn.

Keywords: APCI/MS/MS, DNA adducts; Ion trap; CAD; Biomarkers; Oxidative stress; 4-Hydroperoxy-2-nonenal; Ethenodeoxyguanosine adducts; Nucleosides;

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Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry

Liu, Z.(1), Floss, H.G.(3), Cassady, J.M.(1), Chan, K.K.(*1,2)

(1) Coll. Pharm., (2) Coll. Med. Public Health, Ohio State Univ., Columbus, OH 43210, (3) Dept. Chem., Univ. Washington, Seattle, WA 98195, USA

REF: J. Mass Spectrom. 40(3) 2005 389-399

MS: Finnigan LCQ, ESP, pos., CAD, MSn.

Keywords: Electrospray/MS/MS, drugs; Ion trap; CAD; Maytansine; Ansamitocin P-3; Drugs, metabolism; Microsomal incubate; Plasma; Blood;

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Analysis of Fe(II)-mediated decomposition of a linoleic acid-derived lipid hydroperoxide by liquid chromatography/mass spectrometry

Lee, S.H., Oe, T., Arora, J.S., Blair, I.A.(*)

Cent. Cancer Pharmacol., Univ. Pennsylvania Sch. Med., Philadelphia, PA 19104-6160, USA

REF: J. Mass Spectrom. 40(5) 2005 661-668

MS: Finnigan LCQ, APCI, pos.

Keywords: APCI, oxoalkenals; Ion trap; 4,5-Epoxy-2-decenal; 4-Oxo-2-nonenal; 4-Hydroxy-2-nonenal; 4-Hydroperoxy-2-nonenal; Fatty acids, metabolism; Linoleic acid; Hydroperoxyoctadecadienoic acid; Bifunctional electrophiles; Fenton reaction;

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Synthesis of new benzoxazinone derivatives as neuropeptide Y5 antagonists for the treatment of obesity

Torrens, A.(*1), Mas, J.(1), Port, A.(1), Castrillo, J.A.(1), Sanfeliu, O.(1), Guitart, X.(2), Dordal, A.(2), Romero, G.(2), Fisas, M.A.(2), Sanchez, E.(2), Hernandez, E.(2), Perez, P.(2), Perez, R., Buschmann, H.(1)

(1) Dept. Discovery Chem., (2) Dept. Discovery Biol., Lab. Dr. Esteve SA, Av. Mare de Deu de Montserrat 221, 08041 Barcelona, Spain

REF: J. Med. Chem. 48(6) 2005 2080-2092

MS: Finnigan LCQ Deca XP, APCI, pos.

Keywords: APCI, drugs; Ion trap; Benzoxazinones;

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Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach

Aureli, L.(1), Cruciani, G.(2), Cesta, M.C.(3), Anacardio, R.(4), De Simone, L.(4), Moriconi, A.(*3)

(1) Mol. Discovery Ltd., 4, Chandos St., London W1A 3BQ, UK, (2) Lab. Chemomet. Cheminformat., Univ. Perugia, Via Elce di Sotto 10, 06123 Perugia, (3) Chem. Dept., (4) Anal. Dept., Dompe R&D, Dompe SpA, Via Campo di Pile, 67100 L'Aquila, Italy

REF: J. Med. Chem. 48(7) 2005 2469-2479

MS: Finnigan LCQ Deca XP Plus, ESP, pos., CAD.

Keywords: Electrospray/MS/MS, drugs; Ion trap; CAD; Interleukin inhibitors; Phenylpropionamides; Affinity constant;

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Liquid chromatography-mass spectrometry studies of St. John's wort methanol extraction: active constituents and their transformation

Liu, F.(1), Pan, C.(*1), Drumm, P.(1), Ang, C.Y.W.(2)

(1) Novartis Pharm. Corp., East Hanover, NJ 07936, (2) Natl. Cent. Toxicol. Res., Food Drug Admin., Jefferson, AR 72079, USA

REF: J. Pharm. Biomed. Anal. 37(2) 2005 303-312

MS: Finnigan LCQ Deca, ESP, pos., neg., CAD.

Keywords: Electrospray, drugs; CAD; MS/MS; Ion trap; St. John's wort; Sample preparation; Phloroglucinols; Naphthodianthrones; Hyperforins; Adhyperforin; Hypericins;

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Differential adduction of proteins vs. deoxynucleosides by methyl methanesulfonate and 1-methyl-1-nitrosourea in vitro

Zhang, F.(*), Bartels, M.J., Pottenger, L.H., Gollapudi, B.B.

Toxicol. Environ. Res. Consulting, Dow Chemical Co., 1803 Bldg., Midland, MI 48674, USA

REF: Rapid Commun. Mass Spectrom. 19(4) 2005 438-448

MS: Finnigan LCQ Duo, ESP, pos., CAD.

Keywords: Electrospray/MS/MS, protein adducts; Ion trap; CAD; Deoxynucleoside adducts; Methyl methanesulfonate; Methylnitrosourea; Alkylating agents; Peptides;

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Characterization of phenolic compounds in the Chinese herbal drug Tu-Si-Zi by liquid chromatography coupled to electrospray ionization mass spectrometry

Ye, M.(1), Yan, Y.(2), Guo, D.(*1)

(1) State Key Lab. Nat. Biomimetic Drugs, Sch. Pharm. Sci., Peking Univ., Beijing 100083, (2) Sch. Chinese Materia Medica, Beijing Univ. Chinese Med., Beijing 100102, PR China

REF: Rapid Commun. Mass Spectrom. 19(11) 2005 1469-1484

MS: Finnigan LCQ Advantage, ESP, neg., CAD, MSn.

Keywords: Electrospray/MS/MS, phenolic compounds; CAD; Ion trap; Traditional Chinese medicine; Cuscuta chinensis; Cuscuta australis; Flavonoids; Lignans; Quinic acids; Acyl flavonoid glycosides; Furofurans; Isomer distinction;

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This bibliography was prepared for Thermo Electron Corporation by HD Science Ltd.

last updated 6-JUL-2005