|
Achiral-chiral LC/LC-MS/MS coupling for determination of chiral discrimination effects in phenprocoumon metabolism Kammerer, B.(*1), Kahlich, R.(1), Ufer, M.(1,3), Laufer, S.(2), Gleiter, C.H.(1) (1) Inst. Pharmacol. Toxicol., Dept. Clin. Pharmacol., Univ. Hosp. Tubingen, (2) Inst. Pharm., Dept. Med. Chem., Univ. Tubingen, 72076 Tubingen, Germany, (3) Dept. Lab. Med., Div. Clin. Pharmacol., Karolinska Inst., 17177 Stockholm, Sweden REF: Anal. Biochem. 339(2) 2005 297-309
Keywords: Electrospray/MS/MS, drugs; CAD; Drugs, metabolism; Coumarins; Phenprocoumon; Chiral separation; LC/LC coupling; Mass spectrometric methodology for the determination of glyoxaldeoxyguanosine and O6-hydroxyethyldeoxyguanosine DNA adducts produced by nitrosamine bident carcinogens Dennehy, M.K., Loeppky, R.N.(*) Dept. Chem., Univ. Missouri, Columbia, MO 65211, USA REF: Chem. Res. Toxicol. 18(3) 2005 556-565 MS: Finnigan TSQ 7000, ESP, pos., CAD, SRM. Keywords: Electrospray/MS/MS, DNA adducts; CAD; Nitrosamines; Nitrosodiethanolamine; Nucleoside adducts; Glyoxaldeoxyguanosine; Hydroxyethyldeoxyguanosine; Tissue; Structural and enzymatic parameters that determine alkyl dehydrogenation/hydroxylation of capsaicinoids by cytochrome P450 enzymes Reilly, C.A., Yost, G.S.(*) Dept. Pharmacol. Toxicol., Univ. Utah, Salt Lake City, UT, USA REF: Drug Metab. Dispos. 33(4) 2005 530-536 MS: Finnigan TSQ 7000, ESP, pos., CAD, SRM. Keywords: Electrospray/MS/MS, drugs; CAD; Capsaicinoids, metabolism; Capsaicin; Carrageenans can regulate the pulmonary absorption of antiasthmatic drugs and their retention in the rat lung tissues without any membrane damage Yamada, K.(1,3), Kamada, N.(3), Odomi, M.(3), Okada, N.(1), Nabe, T.(2), Fujita, T.(1), Kohno, S.(2), Yamamoto, A.(*1) (1) Dept. Biopharm., (2) Dept. Pharmacol., Kyoto Pharm. Univ., Misasagi, Yamashina-ku, Kyoto 607-8414, (3) Formulation Res. Inst., Otsuka Pharm. Co. Ltd., 224-18 Ebisuno Hiraishi Kawauchi-cho, Tokushima 771-0182, Japan REF: Int. J. Pharmaceutics 293(1/2) 2005 63-72
Keywords: APCI, drugs; Fluticasone propionate; Steroids; Serum; Carrageenans; Intracellular measurements of anti-HIV drugs indinavir, amprenavir, saquinavir, ritonavir, nelfinavir, lopinavir, atazanavir, efavirenz and nevirapine in peripheral blood mononuclear cells by liquid chromatography coupled to tandem mass spectrometry Colombo, S.(1), Beguin, A.(1), Telenti, A.(2), Biollaz, J.(1), Buclin, T.(1), Rochat, B.(3), Decosterd, L.A.(*1) (1) Div. Pharmacol. Clin., Lab. BH 18-218, Dept. Med., Cent. Hosp. Univ. Vaudois, 1011 Lausanne CHUV, (2) Med. Virol., Inst. Microbiol., (3) Mass Spectrom. Unit Res. Dept., Univ. Hosp. Lausanne, Switzerland REF: J. Chromatogr. B 819(2) 2005 259-276 MS: Finnigan TSQ Quantum, ESP, pos., neg., CAD, SRM. Keywords: Electrospray/MS/MS, drugs; CAD; Indinavir; Amprenavir; Saquinavir; Ritonavir; Nelfinavir; Lopinavir; Atazanavir; Efavirenz; Nevirapine; Blood mononuclear cells; Antiviral drugs; In vitro metabolism of phenoxypropoxybiguanide analogues in human liver microsomes to potent antimalarial dihydrotriazines Shearer, T.W.(*1), Kozar, M.P.(1), O'Neil, M.T.(1), Smith, P.L.(1), Schiehser, G.A.(2), Jacobus, D.P.(2), Diaz, D.S.(1), Yang, Y.-S.(1), Milhous, W.K.(1), Skillman D.R.(1) (1) Walter Reed Army Inst. Res., 503 Robert Grant Ave., Silver Spring, MD 20910, (2) Jacobus Pharm. Co., 37 Cleveland Lane, PO Box 5290, Princeton, NJ 08540, USA REF: J. Med. Chem. 48(8) 2005 2805-2813 MS1: Finnigan TSQ Quantum, ESP, pos., CAD, SRM. Keywords: Electrospray/MS/MS, drugs; CAD; Ion trap; Dihydrotriazines; Triazine metabolites; Phenoxypropoxyguanides, metabolism; Microsomal incubate; Prodrugs; Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons Chen, C.(*), Bazan, N.G. Neurosci. Cent. Excellence, Sch. Med., Louisiana State Univ. Health Sci. Cent., New Orleans, LA 70112, USA REF: J. Neurophysiol. 93(2) 2005 929-941 MS: Finnigan TSQ Quantum, ESP, neg., CAD, SRM. Keywords: Electrospray/MS/MS, prostaglandins; CAD; Tissue; Screening of anabolic steroids in horse urine by liquid chromatography-tandem mass spectrometry Yu, N.H., Ho, E.N.M., Leung, D.K.K., Wan, T.S.M.(*) Racing Lab., Hong Kong Jockey Club, Sha Tin Racecourse, Sha Tin, NT, Hong Kong, PR China REF: J. Pharm. Biomed. Anal. 37(5) 2005 1031-1038 MS: Finnigan TSQ Quantum, ESP, pos., CAD, SRM. Keywords: Electrospray/MS/MS, drugs of abuse; CAD; Anabolic steroids; Urine; Forensic; Resolution, quantification and confirmation of betamethasone and dexamethasone in equine plasma by liquid chromatography/tandem mass spectrometry Luo, Y.(1), Uboh, C.E.(*1,2), Soma, L.R.(1), Guan, F.(1), Rudy, J.A.(2), Tsang, D.S.(1) (1) Dept. Clin. Studies, Sch. Veterin. Med., Univ. Pennsylvania, New Bolton Cent. Campus, Kennett Sq., PA 19348, (2) PA Equine Toxicol. Res. Lab., Dept. Chem., West Chester Univ., West Chester, PA 19382, USA REF: Rapid Commun. Mass Spectrom. 19(6) 2005 825-832
Keywords: Electrospray/MS/MS, drugs of abuse; CAD; Betamethasone; Dexamethasone; Corticosteroids; Glucocorticoids; Equine plasma; Forensic; Simultaneous analysis of twenty-one glucocorticoids in equine plasma by liquid chromatography/tandem mass spectrometry Luo, Y.(1), Uboh, C.E.(*1,2), Soma, L.R.(1), Guan, F.(1), Rudy, J.A.(2), Tsang, D.S.(1) (1) Dept. Clin. Studies, Sch. Veterin. Med., Univ. Pennsylvania, New Bolton Cent. Campus, Kennett Sq., PA 19348, (2) PA Equine Toxicol. Res. Lab., Dept. Chem., West Chester Univ., West Chester, PA 19382, USA REF: Rapid Commun. Mass Spectrom. 19(10) 2005 1245-1256
Keywords: Electrospray/MS/MS, drugs of abuse; CAD; Betamethasone; Dexamethasone; Corticosteroids; Glucocorticoids; Equine plasma; Forensic; This bibliography was prepared for Thermo Electron Corporation by HD Science Ltd. last updated 6-JUL-2005 |
|