MASS SPECTROMETRY BOOKS

Ashcroft Baer Barker Boutton Chapman Cole Cotter Dawson De Hoffmann Evans Harrison Holland Johnstone Lee Lubman March March March McLafferty Montaser Platzner Prokai Russell Schlag Scott Smith Sparkman Tanner Vertes Wampler Watson Yinon Yinon

PROTEINS, PEPTIDES, BIOMEDICAL, LIPIDS, CLINICAL, DRUGS: Burlingame Caprioli Caprioli Chapman Cotter Desiderio Desiderio Ens Fenselau Fox Goad Gross Hancock Hounsell Karger Karger Larsen Lawson Liu McCloskey Makin Marshak Matsuo Murphy Reid Siuzdak Smith Snyder Walker

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Ionization Methods in organic Mass Spectrometry
A.E. Ashcroft
This book concentrates on instrumental operation and gives step-by-step instructions on how to set up mass spectrometers using various ionization types. APCI, electrospray, EI, CI, FAB, fast ion bombardment ionization (including continuous-flow), field desorption, field ionization, thermospray, and MALDI are included.
Order No.: B-0132, 175 pp 1997 £60.00 / $124.95
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Large Ions. Their Vaporisation, Detection and Structural Analysis
T. Baer, C.Y. Ng, I. Powis (Editors)
This book includes chapters on: Investigations of large ions by Fourier transform mass spectrometry; Steps towards a more refined picture of the matrix function in UV-MALDI; Models for matrix-assisted laser desorption and ionization; MALDI; Laser ejections of oligonucleotides; Collisional activation of large molecules.
Order No.: B-0133, 198 pp 1996 £105.00 / $195.00
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Mass Spectrometry. 2nd Edition
J. Barker
This is the second edition of this ACOL open learning text, that continues to provide the analyst with an excellent introduction to mass spectrometry. It adopts a practical approach to self-learning in which the theoretical and operational aspects are combined. Material from the first edition has been expanded and reorganized to bring it up to date. The basic theory of ion formation and behaviour, instrumentation and the interpretation of spectra of simple organic compounds using particle beam, continuous-flow, electrospray and ion spray interfaces are covered.
Order No.: B-0134, 564 pp 1998 £49.50 / $84.95 (softback); Order No.: B0134, 1998 £85.00 / $160.00 (hardback)
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Mass Spectrometry of Soils
T.W. Boutton, S.-I. Yamasaki (Editors)
This well-integrated, single-source reference-the first interdisciplinary work of its kind on the subject- provides detailed coverage of the applications of proven spectrometric techniques in soil science. Presents analytical approaches important in the study of pool sizes and the dynamics of macro and micronutrients, the structure and function of soil organic matter, and the coevolution of soils, plant communities, and climate! Offering highly interdisciplinary perspectives from soil science, ecology, geology, chemistry, biogeochemistry, agronomy and physics. Containing nearly 1200 bibliographic citations, figures, and equations, Mass Spectrometry of Soils is a practical resource for soil scientists, agronomists, ecologists, analytical chemists and biogeochemists, crop scientists, hydrologists, archeologists, and graduate and continuing-education students in these disciplines.
Order No.: B-0135, 536 pp 1996 £155.00 / $220.00
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Practical Organic Mass Spectrometry, 2nd Edition
J.R. Chapman
A fully updated edition including TOF and Fourier Transform instrumentation; expansion of the LC/MS section; new section on SFC/MS; a new chapter on "in-solution" ionization techniques and their use in LC/MS coupling. Approx. 100 more pages than in first edition. "....an excellent textbook...." Anal. Chim. Acta
Order No.: B-0160, 288 pp 1993 £39.95 / $75.00 (paperback)
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Electrospray Ionization Mass Spectrometry: Fundamentals, Instrumentation, and Applications
R.B. Cole (Editor)
Presents a wide view of the current knowledge of the basic aspects of electrospray ionization mass spectrometry. It is divided into 4 main sections, covering fundamental and mechanistic aspects of the electrospray process; coupling electrospray to various mass analyzers; interfacing electrospray to separation techniques; applications to biochemistry.
Order No.: B-0165, 592 pp 1997 £95.00 / $119.95
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Time-of-flight Mass Spectrometry. ACS Symposium Series No. 549
R.J. Cotter
A comprehensive discussion of time-of-flight (TOF) mass spectrometry examining the use of TOF instruments in tandem mode and their interfacing with continuous ionization techniques.
Order No.: B-0170, 233 pp 1994 £59.00 / $85.00
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Quadrupole Mass Spectrometry and its Applications
P.J. Dawson
Originally published in 1976, this standard introduction to quadrupole mass spectrometry gives a broad overview of the development and uses of quadrupoles. It covers basic operating principles, their use in quadrupole mass filters, monopoles, 3D quadrupole ion traps, and time of flight instruments. Some early applications are also given.
Order No.: B-0210, 1976 (reprinted 1995) £70.00 / $94.00
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Mass Spectrometry and its Applications
E. De Hoffmann, J. Charette, V. Stroobant
This is an introductory book aimed at students, technicians and practising analytical scientists in the chemical, biological and biochemical sciences. It introduces the reader to the basics of mass spectrometry, but also contains coverage of many important modern techniques, such as electrospray ionisation and matrix assisted laser desorption ionisation, and of modern instrumentation. Most importantly, it contains guidance for the investigator who wishes to undertake investigations in the fields of (I) applications of mass spectrometry to biological molecules (II) analysis of complex mixtures and (III) analysis of samples that require derivatization, chromatography and/or tandem analysis.Contents: Introduction; Ion Sources; Mass Analysers; Mass Spectrometry Chromatography Coupling; Tandem Mass Spectrometry (MS/MS); Analytical Information; Fragmentation Reactions; Analysis of Biomolecules; Exercises; Appendix.
Order No.: B-0215, 392pp 1996 £85.00 / $165.00 (hardback), Order No.: B-0217, £39.95 / $79.95 (paper)
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Inductively Coupled and Microwave Induced Plasma Sources for Mass Spectrometry
E.H. Evans, J.J. Giglio, T.M. Castillano, J.A. Caruso
This book looks at the most popular and widely used plasma sources - inductively coupled plasma. It shows the problems associated with the method, such as spectral overlap from polyatomic ions and the inefficiency of element ionization by plasmas formed with argon. Alternative gases to highly purified argon are discussed, as well as microwave induced plasmas. The book looks at how the primary mass spectrometric applications solve problems of this sort, and includes the following discussions: interfacing atmospheric plasmas with mass spectrometry; atomization and ionization characteristics; polyatomic ion interferences; interfacing chromatographic techniques. Practical application of the theory is presented in a tutorial style, for the most important research in the field.
Order No.: B-0235, 108 pp 1995 £49.50 / $99.95
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Chemical Ionization Mass Spectrometry, 2nd Edition
A.G. Harrison
A comprehensive review of CI MS applications in structural elucidation and quantitative analytical studies. CI mass spectra of 13 classes of compounds are discussed in detail to illustrate the influence of functional groups on the spectra observed.
Order No.: B-0270, 208 pp 1992 £125.00 / $169.00
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Applications of Plasma Source Mass Spectrometry
G. Holland, A.N. Eaton (Editors)
Represents the current state of plasma source mass spectrometry in all its forms. It looks at the whole range of applications, including environmental, biological/biomedical, industrial, nuclear and geological. Special attention is given to ICP/MS.
Order No.: B-0280, 244 pp 1993 £79.00 / $140.00
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Mass Spectrometry for Chemists and Biochemists, Second Edition
R.A.W. Johnstone and M.E. Rose
This second edition includes new methods and applications that have developed in the past ten years. Powerful methods combining mass spectrometry with newer separation techniques and analysis of once difficult polar and large-mass compounds such as proteins are discussed. CONTENTS: Introduction; Acknowledgements; Table of quantities; List of abbreviations; 1. The mass spectrum; 2. Instrument design; 3. Methods of ionization; 4. Computers in mass spectrometry: data systems; 5. Combined chromatography and mass spectrometry; 6. Uses of derivatization; 7. Quantitative mass spectrometry; 8. Metastable ions and mass spectrometry; 9. Theory of mass spectrometry; 10. Structure elucidation; 11. Examples of structure elucidation by mass spectrometry; 12. Further discussion of selected topics; Bibliography; Index.
Order No.: B-0285, 523 pp 1996 £109.95 / $145.00 (hardback), Order No.: B-0287, £45.50 / $65.95 (paperback)
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A Beginner's Guide to Mass Spectral Interpretation
T.A. Lee
This book is dedicated to the interpretation of mass spectra and deliberately excludes information on hardware and experimental conditions, which may be of limited use in the interpretation. It is aimed at under- and post-graduate level. Each chapter concentrates on a different class of compound, such as hydrocarbons, halocarbons, alcohols, ethers and phenols, aldehydes and ketones, N-containing compounds, thiols and thio ethers and heterocyclic compounds.
Order No.: B-0293, 200 pp 1998 £59.95 / $109.95
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Lasers and Mass Spectrometry. Oxford Series in Optical and Imaging Sciences No. 1
D.M. Lubman (Editor)
Each chapter deals with a particular application area and should be sufficient to form an entry point for the utilization of mass spectrometry for graduate students and researchers. "A good reference source for those working with lasers and for those interested in the advances in chemical analysis afforded by the coupling of these techniques." Anal. Chem. 63, 1991.
Order No.: B-0300, 558 pp 1990 £89.95 / $120.00
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Ion Trap Practical Aspects of Ion Trap Mass Spectrometry. Volume I. Fundamentals of Mass Spectrometry
R.E. March, J.F.J. Todd (Editors)
An account of the development and theory of the quadrupole ion trap, its utilization as an ion storage device, a reactor for ion/molecule reactions and as a mass spectrometer. Four chapters cover the fundamental aspects, including theory, development, operating principles and the production of the first commercial version. Four more chapters cover the environment within the ion trap, including collisional cooling, ion trajectory simulations, boundary excitation and ion/molecule reactions.
Order No.: B-0310, 430 pp 1995 £131.00 / $185.00
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Practical Aspects of Ion Trap Mass Spectrometry. Volume II. Ion Trap Instrumentation
R.E. March, J.F.J. Todd (Editors)
This volume covers the diverse research and applications of ion trap instruments, often in tandem with other instruments or components, such as external ion sources and lasers. The book covers high resolution mass spectrometry and mass measurement accuracy, ion trap confinement of externally generated ions, including by electrospray, ion structure differentiation, lasers, and ion traps in the study of physics.
Order No.: B-0311, 320 pp 1995 £131.00 / $185.00
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Chemical, Environmental and Biomedical Applications of Ion Trap Mass Spectrometry
R.E. March, J.F.J. Todd (Editors)
The book consists of 14 chapters in 4 parts. Part I: Fundamentals (Ion trap theory and design, Ion traps as tandem mass spectrometers, Review of modern ion trap research) Part II: Practical ion trap methodology (GC/MS and GC/MS/MS, LC/MS, Ion spray LC/MS and CE/MS on a modified benchtop ion trap mass spectrometer, Chemical ionization) Part III: Applications involving small molecules (Energetics and CID efficiencies in the quadrupole ion trap, Ion structure studies, Atmospheric glow discharge/ion trap MS, Dynamically programmed scans) Part IV: Environmental and Biomedical Applications (Environmental analyses, Multi-residue pesticide analysis, Electrospray/ion trap MS: Applications to trace analysis).
Order No.: B-0312, 518 pp 1995 £115.00 / $150.00
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Interpretation of Mass Spectra, Fourth Edition
F.W. McLafferty, F. Turecek
An invaluable teaching aid, the fourth edition will be even better than its successful predecessors.
Order No.: B-0360, 370 pp 1993 £39.95 / $49.00
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Inductively Coupled Plasma Mass Spectrometry. From A to Z
A. Montaser
This book covers new instrumentation, theory and applications of ICP-MS. Fundamental applications, sample introduction, RF generators, and comparisons with other plasma mass spectrometric systems are covered.
Order No.: B-0365, 992 pp 1998 £115.00 / $175.00
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Modern Isotope Ratio Mass Spectrometry
I.T. Platzner
All modern developments in isotope ratio mass spectrometry are discussed, with special reference to technical details and instrumentation. Examples from analytical chemistry, astronomy, geochemistry and biomedical science are included. There is a comprehensive elemnt-by-element review of 94 elements. An applications chapter and an instrumentation chapter are also included.
Order No.: B-0368, 530 pp 1997 £150.00 / $285.00
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Field Desorption Mass Spectrometry
L. Prokai
Practical Spectroscopy Series, Vol. 9 (Series Editor, E. Brame, Jr., CECON Group, Wilmington). Principles: Field ionization - removal of electrons by tunnelling; Mechanism of ion formation under field desorption conditions; Field ionization mechanism; Field-induced extraction of ions from electrolytic solutions and salt layers; Thermal ionization mechanism; Experimental techniques and methods: Ion emitters; Instrumentation; Special techniques; General practice: FD operation; Chemistry on the emitter; Structural information from FD MS; Quantitative analysis; FD in comparison with other ionization methods; Applications: Pharmaceutical chemistry, biochemistry and medicine; Environmental analysis; Fossil fuels and petrochemicals; Inorganic and organometallic compounds; Polymers.
Order No.: B-0380, 304 pp 1990 £125.00 / $185.00
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Experimental Mass Spectrometry
D.H. Russell (Editor)
Designed as a guide for nonspecialists, provides a thorough discussion of the latest developments in this field. The major areas of modern biological mass spectrometry are addressed, as well as: negative ion chemistry and organo-alkali metal ions; collision-induced dissociation in tandem/structural mass spectrometry; fundamental aspects of Fourier transform ion cyclotron resonance mass spectrometry; aspects of protein structure using time-of-flight based methods; electrospray ionization and liquid chromatography.
Order No.: B-0410, 325 pp 1994 £89.00 / $129.00
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Time-of-Flight Mass Spectrometry and its Applications
E.W. Schlag
Previously published as a special issue of the journal International Journal of Mass Spectrometry and Ion Processes (1994). Gives a survey of current applications from many active groups in the field.
Order No.: B-0420, 420 pp 1994 £110.00 / $169.00
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Tandem Techniques
R.P.W. Scott
The functions and uses of instruments combining separation and identification techniques for analyzing mixtures are described. The interfaces are described in details and comparative performance data is presented. The techniques include GC/MS and LC/MS.
Order No.: B-0421, 538 pp 1997 £79.00 / $150.00
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Understanding Mass Spectra
R.M. Smith & K.L. Busch
This text provides a basic understanding of the interpretation of mass spectra and fundamental practical information. It serves as a textbook and as a self-learining tool. It includes a basic overview of theory and instrumentation, with "non-intimidating" mathematical explanations, several chapters on interpretation, real-life problems and examples, answers to problems with explanations and lists and tables of useful information.
Order No.: B-0422, 290 pp 1998 £49.00 / $75.00
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Mass Spec Desk Reference
O. David Sparkman
A compilation of correct and incorrect terms used in mass spectrometry along with some historical background. Also contains a bibliography of books, software, monographs and current journals relating to mass spectrometry. "I am pleased to recommend and comment on this publication by my life-long friend and colleague...The Mass Spec Desk Reference gives an excellent overview to, as well as specific details on, the language and scientific communication media used in the active world of mass spectrometry" Dr. J. Throck Watson, Professor, Michigan State University.
Order No.: B-0426, 106 pp 2000 £35.00 / $45.00
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Plasma Source Mass Spectrometry. Developments and Applications
S.D. Tanner & J.G. Holland (Editors)
This book is a unique presentation of the most recent developments in plasma source mass spectrometry. Discussions include various methods of mass analysis, data analysis strategies, plasma dynamics and the results of analyses in areas such as drinking water contamination, landfill groundwater contamination and nuclear materials processing. Instrumentation developments, the use of chromatography and interferences are also covered.
Order No.: B-0423, 330 pp 1997 £80.00 / $150.00
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Laser Ionization Mass Spectrometry
A. Vertes, R. Gijbels, F. Adams (Editors)
Takes a comprehensive look at the new hardware and investigative possibilities of this form of analysis. It links theory with applications and provides chemists using mass spectrometry with a definitive guide to laser ionization MS.
Order No.: B-0440, 582 pp 1993 £140.00 / $160.00
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Applied Pyrolysis Handbook
T.P. Wampler (Editor)
Contents: Analytical pyrolysis: an overview; Instrumentation and analysis; Pyrolysis mass spectrometry: instrumentation, techniques and applications; Microstructure of polyolefins; Degradation mechanisms of condensation polymers; The application of analytical pyrolysis to the study of cultural materials; Environmental applications of pyrolysis; Examination of forensic evidence; Characterization of microorganisms by pyrolysis-GC, pyrolysis-GC/MS and pyrolysis-MS. Analytical pyrolysis of polar micromolecules; Index of sample pyrograms.
Order No.: B-0460, 376 pp 1995 £125.00 / $185.00
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Introduction to Mass Spectrometry, Third Edition
J.T. Watson
Completely revised and updated in the Third Edition, this text provides an easy-to-read guide to the concept of Mass spectrometry and demonstrates its potential and limitations. Utilizing "real-life examples" of analyses and applications the book presents eighteen realistic cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analyzers and ionization, along with corresponding strategies for interpretation of data. Detailed coverage of inlet systems, vacuum systems, detectors, data systems, and specialized techniques such as MS/MS and selected ion monitoring for quantitative analyses is included. This new edition also contains eight new chapters, including six devoted to various types of ionization such as Electrospray, MALDI and ICP. There is also an extensive coverage of electron ionization incorporating a thorough introduction to a variety of types of fragmentation and fragmentation pathways in different classes of compounds.
Order No.: B-0470, 450 pp 1997 £95.00 / $119.00
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Forensic Applications of Mass Spectrometry
J. Yinon
The techniques discussed include capillary GC/MS, thermospray LC/MS, tandem MS and pyrolysis. A variety of applications include analysis of body fluids and hair for drugs of abuse, drug testing in sports, analysis of accelerants in fire debris and protection of industrial products by isotopic signature.
Order No.: B-0490, 320 pp 1995 £89.00 / $125.00
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Modern Methods and Applications in Analysis of Explosives
J. Yinon and S. Zitrin
Discusses new developments in techniques and methods for the analysis of explosives and reviews recent applications. Contains a list of explosive compounds based on a survey of specialist laboratories all over the world. Contents: Explosive compounds and mixtures; Chromatographic methods; Mass spectrometric methods; Analysis of expolsive residues; Environmental analysis of explosives; Detection of hidden explosives.
Order No.: B-0500, 316 pp 1993 £110.00 / $255.00 (cloth); Order No.: B-0505, £59.95 / $99.95 (paper)
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PROTEINS, PEPTIDES, BIOMEDICAL, LIPIDS:

Mass Spectrometry in the Biological Sciences
A.L. Burlingame & S.A. Carr (Editors)
Leading practitioners describe in detail advanced methods used in the analysis of biomacromolecules of natural and recombinant origin. They cover real-world problems in protein biochemistry, immunology, glycobiology and in the biochemistry of human bacterial pathogens, lipids and nucleic acids. The MS methods include MALDI TOF MS, electrospray, tandem techniques and FT/ICR. Database searching is also covered. A series of 10 appendices list useful reference data for the mass spectrometry of peptides and carbohydrtaes.
Order No.: B-0153, 584 pp 1996 £150.00 / $219.00
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Mass Spectrometry in Biomolecular Sciences
R.M. Caprioli, A. Malorni, G. Sindona (Editors)
This volume covers the Proceedings of the NATO Advanced Study Institute held in 1993 at Lacco Ameno, Ischia, Italy. It covers technological and applied developments and includes ionization techniques and ion analysis. The newer ionization methods are reviewed and major instrumentation involved in mass analysis is described. The online combination of GC, LC and SFC with mass spectrometry is also included.
Order No.: B-0161, 548 pp 1996 £199.00 / $299.00
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Selected Topics in Mass Spectrometry in the Biomolecular Sciences
R.M. Caprioli, A. Malorni, G. Sindona (Editors)
This volume covers the Proceedings of the NATO Advanced Study Institute held in Altavilla-Milicia, Italy in 1996. Many fundamental aspects of mass spectrometry are presented, including the principles and applications of electrospray, ion spray, MALDI, GC/MS interfaces and tools for quantitative analysis. The major part of the book deals with peptides, proteins, oligonucleotides, DNA adducts, polysaccharides, lipids, and plant metabolites.
Order No.: B-0162, 612 pp 1997 £220.00 / $335.00
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Protein and Peptide Analysis by Mass Spectrometry
J.R. Chapman (Editor)
Contains a comprehensive collection of mass spectrometry methods for the analysis of peptides and proteins. Experts have contributed detailed step-by-step protocols covering topics such as recombinant protein analysis, peptide sequencing and quantification, analysis of glycoproteins and glycopeptides, measurement of drug loading on proteins, study of protein secondary structure, noncovalent interactions and using mass spectrometry with PAGE.
Order No.: B-0163, 352 pp 1996 £79.00 / $99.50
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Time of Flight Mass Spectrometry. Instrumentation and Application to Biological Research
R.J. Cotter
The basic principles of time-of-flight mass spectrometry are presented with a strong emphasis on biological research. Techniques such as orthogonal extraction, post source decay and delayed extraction and the various compatible ionization techniques (SIMS, FAB, plasma desorption, laser desorption, MALDI and electrospray) are covered. Applications to peptides, proteins, oligonucleotides and other biological molecules and the use of the technique in human genome sequencing are featured.
Order No.: B-0166, 1997 £99.00 / $149.00; allow 4-6 weeks for delivery in Europe
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Mass Spectrometry. Clinical and Biomedical Applications. Volume 1
D.M. Desiderio (Editor)
Offers a thorough exploration of significant advances in theoretical and experimental research and instrumentation. Contents: Electrospray MS: principles and methods; Analysis of biomolecules by electrospray MS and MS/MS; Analysis of muscle relaxants by MS methods; Quantitative analytical MS of endogenous neuropeptides in human pituitaries; Neurotransmitters; Cannabinoids; Inborn errors of amino acid and organic acid metabolism; Carnitine and acylcarnitines in metabolic disease diagnosis and management; Platelet-activating factor and related compounds; Index.
Order No.: B-0220, 368 pp 1992 £85.00 / $125.00
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Mass Spectrometry. Clinical and Biomedical Applications. Volume 2
D.M. Desiderio (Editor)
Reviews novel instrumentation and techniques as applied to the analysis of diacylglyceryl-phospholipids, modifications to DNA, the characterization of variant haemoglobins and urinary nucleosides. Also featured is a description of a new combined microdialysis/MS technique. Reflects the flexible, broad-based approaches mass spectroscopists apply to clinical and biomedical challenges.
Order No.: B-0230, 254 pp 1994 £85.00 / $125.00
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New Methods for the Study of Biomolecular Complexes
W. Ens, K.G. Standing, I.V. Chernushevich (Editors)
This volume covers the proceedings of the NATO Advanced Study Institute Workshop held in 1996 in Alberta, Canada, on the study and characterization of noncovalent biomolecular complexes by electrospray and MALDI mass spectrometry. Mass spectra of large complexes (several hundred kDa) have been obtained on sector, quadrupole, TOF and ICR instruments. The use of other techniques in combination with mass spectrometry for studying supramolecular complexes is also discussed.
Order No.: B-0233, 368pp 1998 £120.00 / $180.00
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Mass Spectrometry for the Characterization of Microorganisms. ACS Symposium Series No. 541
C. Fenselau (Editor)
The book includes features on GC/MS for the clinical diagnosis of viral infection and summarizes the status of detection of biological agents and of modifications in ribonucleic acids in microorganisms. It also describes electrospray, laser desorption and tandem MS for protein processing and modification in viruses.
Order No.: B-0240, 238 pp 1993 £69.00 / $95.00
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Analytical Microbiology Methods. Chromatography and Mass Spectrometry
A. Fox, S.I. Morgan, L. Larsson, G. Odham
A broad array of useful approaches for automated and rapid identification of microorganisms, characterization of microbial products and constituents, trace detection of microbial chemicals. "Chapters are well written by authors who are clearly at the forefront of research in this field...should be in the library of every practising microbiologist and analytical chemist/biochemist".
Order No.: B-0250, 288 pp 1990 £89.00 / $125.00
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Mass Spectrometry in the Biological Sciences; A Tutorial, Proceedings of the NATO Advanced Study Institute on "Mass Spectrometry in the Molecular Sciences"
M.L. Gross
Contents: Part I, Instrumentation for mass analysis and detection; Sectors and tandem sectors, hybrid tandem MS, triple quadrupole, ion traps, FTMS, TOFMS, ion detection, Part II, Methods in mass spectrometry; electrospray, laser desorption, MALD applications, laser desorption, CI and laser desorption CI with FTMS, plasma desorption, continuous flow FAB, review of LC/MS, SFC/MS, thermospray, neutralization-reionization, gas-phase chemistry, Part III, Applications to biomolecules; haemoglobin variants, post-translational modification of proteins, FAB/MS and MS/MS for post-translational modification in rabbit elongation factor, cockroach neuropeptides, retro-inverso linear peptides, O-linked glycopeptides, nucleosides and oligonucleotides, carcinogen-modified nucleosides, lipids - charge-remote fragmentation, cellular lipids for bacteria classification, phosphatidylinositol from carrot cell membranes.
Order No.: B-0260, 528 pp 1992 £190.00 / $275.00
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Handbook of Sterol Analysis
J. Goad, T. Akihisa
An authoritative guide to the extraction, separation and analysis of sterols, with an emphasis on plant sterols. Sources of sterols and methods of laboratory synthesis are covered, and the book ends with chromatographic and spectral data of representative natural sterols. An extensive list of references is included. CONTENTS: Introduction to sterol structure, biochemistry and nomenclature. Extraction of sterols from tissues. Initial separation methods. HPLC methods. Gas chromatography methods. Ultra-violet and infra red spectroscopy. Mass spectrometry and GC-MS. 1H and 13C NMR spectroscopy. Methods of sterol quantification. Analysis of sterols of clinical significance. Sources of sterols. Chemical synthesis of sterols. Tables of physical data. References. Index.
Order No.: B-0255, 352 pp 1995 £120.00 / $199.00
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New Methods in Peptide Mapping for the Characterization of Proteins
W.S. Hancock (Editor)
A Volume in the Analytical Biotechnology Series. This text is devoted to the characterization of recombinant DNA-derived proteins by peptide mapping. It describes new technological procedures including capillary electrophoresis, analysis of glycopeptides and the use of electrospray and matrix-assisted laser desorption mass spectrometry. The book presents practical procedures for preparing a protein sample, the enzyme digestion, choice of separation methods and procedures for the structural analysis of the separated species. Many figures of peptide maps illustrate typical results. Tables of summary information about digestion, separation conditions and analyses of important protein samples are also presented.
Order No.: B-0265, 272pp 1995 £99.00 / $149.95; allow 6-12 weeks for delivery in Europe
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Glycoanalysis Protocols
E. Hounsell (editor)
This book is a follow up to Dr. Hounsell's previous book, Glycoprotein Analysis in Biomedicine. Physicochemical aspects of analysis are emphasised in order to appeal to the increasing sophistication of researchers in the field. Coverage includes mass spectrometry of oligosaccharides, NMR, and computer-aided molecular modelling. All of the necessary analytical techniques are described, allowing for extensive research into the structure and function of glycosylation.
Order No.: B-0285, 380pp 1996 £69.00 / $89.00
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Methods in Enzymology. Volume 270. High Resolution Separation and Analysis of Biological Macromolecules, Part A
B.L. Karger & W.S. Hancock (Editors)
With its companion Volume 271, they cover the fundamentals and applications of LC, electrophoresis and mass spectrometry, with chapters written by experts in their fields. The MS chapters cover Fast atom bombardment mass spectrometry (Seifert & Caprioli), Electrospray ionization mass spectrometry (Banks & Whitehouse), Matrix-assisted laser desorption mass spectrometry of proteins (Beavis & Chait), Quadrupole ion trap mass spectrometry (Schwartz & Jardine).
Order No.: B-0287, 1996 £89.00 / $126.00
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Methods in Enzymology. Volume 271. High Resolution Separation and Analysis of Biological Macromolecules, Part B
B.L. Karger & W.S. Hancock (Editors)
With its companion Volume 270, they cover the fundamentals and applications of LC, electrophoresis and mass spectrometry, with chapters written by experts in their fields. The MS chapters cover Protein structure analysis by mass spectrometry (Yates), Carbohydrate sequence analysis by electrospray ionization-mass spectrometry (Reinhold, Reinhold & Chan), Reversed-phase peptide mapping of recombinant human glycoproteins using liquid chromatography/electrospray ionization-mass spectrometry (Hancock et al.), Peptide characterization by mass spectrometry (Gillece-Castro & Stults), Capillary electrophoresis-mass spectrometry (Smith et al.), Trace analysis peptide mapping by high-performance displacement chromatography (Frenz), Measuring DNA adducts by gas chromatography-electron capture-mass spectrometry (Giese et al.).
Order No.: B-0288, 1996 £79.00 / $ 120.00
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Mass Spectrometry of Biological Materials, Second Edition, Revised and Expanded
B.S. Larsen, C.N. McEwen (Editors)
Instrumentation and Ionization Methods for the Analysis of Biological Materials by Mass Spectrometry (McEwen & Larsen); High-Resolution Mass Spectrometry and Accurate Mass Measurements of Biopolymers Using MALDI TOF (Edmondson & Russell); A Novel Geometry Mass Spectrometer, the Quadrupole Orthogonal Acceleration Time-of-Flight Instrument, for Low Femtomole/Attomole Range Biopolymer Sequencing, (Morris et al.); Affinity Techniques Combined with Mass Spectrometry (Wieboldt et al.); Screening Molecular Diversity Using Pulsed Ultrafiltration Mass Spectrometry (van Breemen et al.); Mass Spectrometry in Immunology: Identification of a Minor Histocompatibility Antigen (Walker et al); Strategies for the Rapid Characterization of Recombinant and Native Proteins by Mass Spectrometry (Kassel et al.); Mass Spectrometry in Drug Discovery (Moseley et al.); Analysis of Glycoproteins (Orlando & Yang); Analysis of Phosphorylated Proteins by Mass Spectrometry (Dass); Mass Spectrometry-Based Approaches Toward the Study of Regulated Biological Systems (watts et al.); Gels in Vacuo? A Minimalist Approach for Combining Mass Spectrometry and Polyacrylamide Gel Electrophoresis (Loo et al.); Studying Noncovalent Interactions by Electrospray Ionization Mass Spectrometry (Loo & Sannes-Lowery); Protein-Protein and Protein-Ligand Interactions Studied by Hydrogen/Deuterium Exchange Mass Spectrometry (Robinson); Characterization of Oligonucleotides by Electrospray Mass Spectrometry (Cram); Methods and Applications of Sizing DNA by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (Lubman et al.); Network-Based Biomformatics in Protein Mass Spectrometry (Fenyo & Beavis).
Order No.: B-0351, 488 pp 1998 £155.00 / $230.00
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Mass Spectrometry in Clinical Biochemistry
A.M. Lawson (Editor)
An advanced review and reference handbook of the current and potential applications of mass spectrometry to the practice of clinical biochemistry. Applications to the work of specialized laboratories are discussed covering subjects such as endocrinology, psychiatry, paediatrics, immunology, nutrition and others that embrace clinical biochemistry. Present trends that include simplified instrumentation and the introduction of new multisector instrument techniques are described. The multi-author nature of the book has enabled authoritative overviews of each compound class and a realistic assessment of the future scope of mass spectrometry to clinical chemistry and biochemistry. Contents: Mass spectrometry - the fundamental principles; Bile acids; Biogenic amines; Carbohydrates; Lipids; Organic acids; Endogenous brain peptides; Porphyrins and bile pigments; Prostaglandins; Purines and pyrimidines; Steroids; Thyroid hormones; Reference methods; Stable isotopes in clinical investigation.
Order No.: B-0290, 745 pp 1989 £165.00 / $290.00
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Handbook of Drug Analysis Applications in Forensic and Clinical Laboratories
R.H. Liu, D.E. Gadzala
This book should be regarded as an essential requirement for forensic toxicologists, crime laboratory technicians, clinical chemists and medicinal toxicologists. It covers preliminary test and chromatographic methods in forensic drug testing, reviews identification methods such as molecular spectrophotometry, nuclear magnetic resonance, and mass spectrometry, and discusses the fundamental relationship between instrumentation and drug analysis. It also evaluates the characteristics and pretreatment approaches for common sample categories, presents for convenient reference a systematic summary of basic information and metabolites of common drugs, and provides proven laboratory procedures for the analysis of commonly abused drugs. Finally it presents in-depth test result interpretation on issues commonly encountered in workplace drug urinalysis, and analyzes and compares performance characteristics of immunoassays commonly used for workplace drug urinalysis.
Order No.: B-0293, 385 pp 1997 £114.00 / $ 159.00; allow 6-8 weeks for delivery in Europe
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Steroid Analysis
H.L.J. Makin, D.B. Gower, D. Kirk (Editors)
This landmark volume, written by a team of distinguished authors, provides comprehensive and up-to-date information on the analysis of steroids, mainly in biological fluids. Chapters on the extraction, separation and quantitation of steroids are followed by chapters describing the analysis of specific steroid groups. The emphasis is on problems arising from the lower levels of analytes in complex matrices. CONTENTS The structure and nomenclature of steroids. Spectroscopic methods of steroid analysis. General methods for the extraction, purification and measurement of steroids by HPLC, GLC, MS and immunoassay. Analyses of corticosteroids, corticosteroid metabolites and related compounds in body fluids and tissues. Extraction, purification and estimation of the androgens and their derivatives. Analyses of progestogens. The measurement of oestrogens. Anabolic steroids: metabolism, doping and detection in equestrian and human sports. Assay of bile acids in biological samples. Analysis of vitamin D, its metabolites and structural analogues. Phytosteroids. The quality assessment of steroid hormone assays. Index.
Order No.: B-0305, 736 pp 1995 £225.00 / $375.00
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Techniques in Protein Chemistry. VIII
D.R. Marshak (Editor)
The next in this series, this book is is a valuable bench-top reference tool for protein chemists, featuring the most up-to-date advances in protein methodologies in the areas: Protein sequencing and analysis; Mass spectral analysis of peptides and proteins; Posttranslational processing of proteins; High-sensitivity protein and peptide separations; Protein folding and NMR; Functional domain analysis; Protein design and engineering.
Order No.: B-0308, 1997 £115.00 / $155.00
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Biological Mass Spectrometry. Present and Future
T. Matsuo, R.M. Caprioli, M.L. Gross, Y. Seyama (Editors)
This volume covers the recent developments in the field of biological mass spectrometry, including electrospray ionization and matrix-assisted laser desorption, LC/MS ion trap mass spectrometry and FT/ICR. Contents: Introduction to modern biological mass spectrometry; New instrumentation and methodologies; New applications (Peptides and proteins, Oligosaccharides and lipids, Nucleic acids, Xenobiotics and metabolites, Environmental and endogenous toxic compounds, Analytical and organic chemistry).
Order No.: B-0330, 684 pp 1994 £155.00 / $488.00
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Methods in Enzymology, Vol. 193, Mass Spectrometry
J.A. McCloskey (Editor)
With 70 expert contributors, this volume represents considerable value for those engaged in a variety of structural biology studies. The first section covers a range of general techniques and topics of contemporary importance in the applications of MS to the biological sciences in general. The 3 remaining sections emphasize specific applications divided among three major classes of molecules. Each of these sections opens with a critical overview of the applications of mass spectrometry to that area. Contents: Introduction; General techniques; Peptides and proteins; Glycoconjugates; Nucleotides and nucleosides; Appendixes (isotopic exact masses and abundances; Reference ions for exact mass measurements; Matrix cluster ions; Calculation of isotopic abundance patterns; Nomenclature for peptide fragment ions; Residue mass for peptides).
Order No.: B-0340, 960 pp 1990 £135.00 / $175.00
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Mass Spectrometry of Lipids
R.C. Murphy
A fundamental overview of the general physical concepts of MS that thoroughly details the unique ion chemistry of specific lipids, ranging from the simple structure of unsaturated fatty acids to more complex glycosphingolipids and glycerophospholipids. CONTENTS: Introduction and MS; Ionization techniques; Sample introduction; Fatty acids; Eicosanoid mass spectrometry; Triacylglycerols, diacylglycerols and monoacylglycerols; Glycerophospholipids; Sphingolipids; Index.
Order No.: B-0370, 282 pp 1993 £79.00 / $109.00
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Methodological Surveys in Bioanalysis of Drugs, Volume 24. Biofluid Assay for Peptide-Related and Other Drugs
E. Reid, H.M. Hill, I.D. Wilson (Editors)
This book describes state-of-the-art technology in the bioanalysis of drugs. The Assay Compendium contains a summary of literature based on therapeutic type, emphasizing more sensitive assays and automation. Approaches described for peptide-related drugs include immuno-based methods and mass spectrometry methods, including MALDI MS, APCI LC/MS, electrospray LC/MS and tandem MS techniques.
Order No.: B-0425, 350 pp 1996 £109.50 / $225.00
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Mass Spectrometry for Biotechnology
G. Siuzdak
Introduces the fundamental concepts of MS and how the instruments work, with descriptions of recent advancements. Key features include a glossary of basic terms, practical tips on using MS techniques and a simplified description of MS incl. MALDI, electrospray and FAB.
Order No.: B-0430 153 pp 1996 £39.00 / $55.00
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Protein Sequencing Protocols
B.J. Smith (Editor)
This book provides practical step-by-step details of techniques utilized for protein sequence analysis. Techniques covered include peptide isolation and mapping, amino acid analysis, chemical and mass spectrometric approaches to N- and C-terminal sequencing, and analysis of sequence information. Protein researchers will utilize this handy one-stop manual to design and carry out their experiments with confidence that the protocols are all laboratory tested and modifiable to suit their own research needs. Includes electrospray and fast atom bombardment mass spectrometry of proteins and peptides.
Order No.: B-0433, 400 pp 1996 £79.00 / $99.50
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Biochemical and Biotechnological Applications of Electrospray Ionization Mass Spectrometry. ACS Symposium Series 619
A.P. Snyder (Editor)
This book introduces improved characterization of proteins and biological molecules. The chapters include specific applications of electrospray ionization mass spectrometry for analyzing proteins, peptides, glycolipids, lipopolysaccharides, oligodeoxynucleotides, nucleic acids, drugs and marine toxins.
Order No.: B-0435, 605 pp 1996 £125.00 / $165.00
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The Protein Protocols Handbook
J.M. Walker (Editor)
This indispensable handbook offers today's most comprehensive protocols for the analysis of proteins and peptides. The multitude of condensed techniques provided cover all of the basic methods regularly employed by researchers of proteins. Concise, yet comprehensive, these techniques are carefully drafted by experts who use them regularly in their lab. 148 concise, step-by-step protocols for the analysis of proteins and peptides. Mainly chromatography and electrophoresis but with some MALDI and GC/MS.
Order No.: B-0450, 660 pp 1996 £104.50 / $149.50 (hardback); Order No.: B-0455, £ 85.00 / $120.00 (comb)
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